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Radiesse® by Merz Pharmaceuticals is a commercial injectable formulation of calcium hydroxylapatite (CAHA). Similar to the calcium mineral found in bone, calcium hydroxylapatite is a compound increasing volume and plumpness for both cosmetic and functional purposes.

Radiesse® Overview - 1164


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The Skinny

Average Recovery

5 days








$650 - $1598


Before & After Images by Provider

Radiesse® Before, Female 33 - 3009Radiesse® After, Female 33 - 3009
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Radiesse® Before, Female 52 - 2612Radiesse® After, Female 52 - 2612
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The Specifics

What is Radiesse®?

Radiesse® by Merz Pharmaceuticals is a specially formulated injectable dermal filler used to smooth fine lines and wrinkles and also improve volume loss in the backs of the hands. Radiesse® is unique in that its primary ingredient is calcium hydroxylapatite (CAHA), which is formulated as calcium microspheres.

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CAHA is believed to both enhance skin volume and plumpness and stimulate the body’s production of natural collagen to provide natural looking, lasting results. Radiesse® is approved by the United States Food and Drug Administration (FDA) to treat moderate to severe facial wrinkles, however, it is also used off-label for volume loss in the backs of the hands. Radiesse® is commonly used to treat:

  • Nasolabial folds (i.e. smile lines)
  • Marionette lines
  • Oral commissures (i.e. corners of the mouth)
  • Pre-jowl fold
  • Chin wrinkles
  • Aging hands

The active ingredient CAHA of Radiesse® is generally believed to provide a more lasting solution than fillers composed of hyaluronic acid like Juvéderm® and Restylane®. Bellafill® and Sculptra® contain alternative primary ingredients and may provide results more comparable to Radiesse®.

What cosmetic concerns does Radiesse® treat?

  1. Fine Lines & Wrinkles: Radiesse® can be used to treat moderate to severe fine lines, wrinkles, and folds.
  2. Aging Hands: Radiesse® can be used to encourage volume restoration in the backs of the hands.
  3. Cheek Volume: CAHA fillers, like Radiesse®, can enhance the contour of the cheek and minimize the appearance of nasolabial folds.
  4. Neck & Jaw Definition: Radiesse® injections along the jawline can contour the jaw and improve the appearance and definition of the neck and jaw.
  5. Chin Shape & Size: CAHA-based fillers can be used to augment the chin and improve protrusion.

Who is the ideal candidate for Radiesse®?

The ideal candidate for a Radiesse® injection is over 18 years old and looking for a safe and effective temporary solution to common facial cosmetic concerns. Radiesse® is not recommended for women who are pregnant or nursing, and anyone with an allergy to the components of Radiesse®.

What is the average recovery associated with Radiesse®?

Most individuals experience minimal recovery with swelling, tenderness, and redness at the injection site lasting one to two days. For some, swelling may persist for a few days. Many candidates resume most all activities directly after the injections.

What are the potential side effects of Radiesse®?

Common side effects of Radiesse® injections include redness, dryness, and flaking. Firmess, tenderness, itchiness, lumps, bumps, possible site infection, and/or bruising/discoloration may occur. A serious complication of a Radiesse® injection is intravascular injection (injection into a blood vessel) leading to skin necrosis. Severe allergic reactions can occur.

What can someone expect from the results of Radiesse®?

Radiesse® results are noticeable immediately following the procedure. Maintenance treatments are generally necessary every six to 12 months depending on the treatment area and individual candidate.

What is the average cost of Radiesse®?

The average cost of Radiesse® is $650 to $1,600. The actual cost of the injection will vary by procedure, location, board certified dermatologist or plastic surgeon, and individual candidate needs. Learn more in our [complete guide to Radiesse® cost](https://aedit.com/procedure/radiesse/cost).


  • Stimulates Collagen
  • Minimally Invasive
  • Semi-permanent


  • Possible Asymmetry
  • Reoccurring Expense

Invasiveness Score


Invasiveness is graded based on factors such as anesthesia practices, incisions, and recovery notes common to this procedure.

What to Expect

Radiesse® injections are simple, outpatient procedures with minimal side effects and downtime. Here is a general guide for what to expect before, during, and after a Radiesse® injection:

The Takeaway

Radiesse® is a calcium hydroxyapatite-based injectable gel dermal filler used to treat both volume loss in the back of the hands and facial cosmetic concerns. The calcium microspheres in Radiesse® provide natural volume and also stimulate collagen production in the body. Radiesse® injections typically have few side effects and short downtime. Results typically last six to 12 months.
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Source List


AEDIT uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read our editorial process to learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.

  1. Luthra, A. “Shaping Lips with Fillers.” J Cutan Aesthet Surg. v.8(3); Jul-Sep 2015.; 2015-07-01
  2. Huang W, Rogachefsky AS, Foster JA Brow Lift with Botulinum Toxin PubMed; 2000-01-01


‘Try on’ aesthetic procedures and instantly visualize possible results with AEDIT and our patented 3D aesthetic simulator.

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